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Rikard Holmdahl Selected Research

Monoclonal Antibodies

5/2022Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst.
1/2018Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells: A Novel Experimental Model of Rheumatoid Arthritis.
6/2011Chemical changes demonstrated in cartilage by synchrotron infrared microspectroscopy in an antibody-induced murine model of rheumatoid arthritis.
11/2010Specific antibody protection of the extracellular cartilage matrix against collagen antibody-induced damage.
1/2007Collagen antibody induced arthritis.
1/2006Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity.
9/2005Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis.
3/2005The plasminogen activator/plasmin system is essential for development of the joint inflammatory phase of collagen type II-induced arthritis.
1/2005Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro.
7/2004Antileukoproteinase: modulation of neutrophil function and therapeutic effects on anti-type II collagen antibody-induced arthritis.
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Rikard Holmdahl Research Topics

Disease

179Arthritis (Polyarthritis)
04/2024 - 01/2002
137Rheumatoid Arthritis
04/2024 - 02/2002
81Experimental Arthritis
02/2024 - 05/2002
56Inflammation (Inflammations)
04/2024 - 01/2002
39Autoimmune Diseases (Autoimmune Disease)
04/2024 - 01/2002
12Psoriasis (Pustulosis Palmaris et Plantaris)
06/2023 - 10/2006
9Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
05/2017 - 07/2002
7Pain (Aches)
02/2024 - 12/2012
7Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2023 - 09/2002
7Neoplasms (Cancer)
01/2022 - 10/2010
6Psoriatic Arthritis
06/2023 - 09/2016
6Infections
12/2022 - 09/2014
6Hypersensitivity (Allergy)
01/2022 - 08/2004
6Multiple Sclerosis
05/2017 - 01/2003
5Pneumonia (Pneumonitis)
01/2023 - 04/2013
5Chronic Granulomatous Disease
12/2014 - 11/2012
4Necrosis
01/2021 - 08/2005
4Colitis
03/2018 - 01/2014
4Relapsing Polychondritis
03/2004 - 01/2002
3Osteoarthritis
11/2022 - 09/2002
3Chronic Disease (Chronic Diseases)
05/2022 - 08/2011
3Pathologic Processes
09/2016 - 01/2010
3Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2016 - 09/2011
2Sepsis (Septicemia)
01/2023 - 07/2010

Drug/Important Bio-Agent (IBA)

93Collagen Type II (Type II Collagen)IBA
06/2023 - 01/2002
64AntibodiesIBA
11/2023 - 09/2002
45Proteins (Proteins, Gene)FDA Link
01/2023 - 01/2002
41CollagenIBA
12/2022 - 01/2002
40Reactive Oxygen Species (Oxygen Radicals)IBA
03/2024 - 09/2005
39AutoantibodiesIBA
02/2024 - 09/2002
38Peptides (Polypeptides)IBA
03/2024 - 01/2003
36EpitopesIBA
01/2023 - 06/2002
33pristane (pristan)IBA
01/2021 - 01/2002
27AntigensIBA
03/2024 - 08/2005
26Immunoglobulin G (IgG)IBA
02/2024 - 09/2002
21NADPH Oxidases (NAD(P)H oxidase)IBA
01/2020 - 01/2003
18CytokinesIBA
01/2023 - 10/2002
15AutoantigensIBA
11/2023 - 01/2002
14Anti-Citrullinated Protein AntibodiesIBA
02/2024 - 01/2010
13neutrophil cytosolic factor 1IBA
04/2024 - 01/2003
13MannansIBA
06/2023 - 09/2014
13Monoclonal AntibodiesIBA
05/2022 - 09/2002
12acetyl 4-aminosalicylic acidIBA
01/2023 - 01/2010
11GlycopeptidesIBA
01/2018 - 12/2002
9T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA
04/2024 - 06/2002
9Antigen-Antibody Complex (Immune Complex)IBA
11/2023 - 07/2004
9Cartilage Oligomeric Matrix ProteinIBA
01/2022 - 01/2002
8Polysaccharides (Glycans)IBA
12/2022 - 10/2007
8Histocompatibility Antigens Class IIIBA
11/2012 - 01/2006
7Rheumatoid FactorIBA
02/2024 - 12/2003
7VaccinesIBA
01/2023 - 10/2010
7T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2022 - 12/2002
6Immunoglobulin M (IgM)IBA
11/2023 - 12/2003
6EnzymesIBA
11/2017 - 03/2006
5NADPH Oxidase 2IBA
10/2023 - 05/2012
5Amino AcidsFDA Link
06/2023 - 09/2002
5Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA
01/2023 - 01/2005
5HLA-DRB1 Chains (HLA DRB1)IBA
01/2022 - 01/2006
5Oxygen (Dioxygen)IBA
01/2020 - 08/2007
5Complement System Proteins (Complement)IBA
10/2013 - 03/2004
4B-Lymphocyte Epitopes (B-Cell Epitope)IBA
01/2023 - 08/2015
4Therapeutic UsesIBA
01/2023 - 07/2004
4Collagen Type XIIBA
01/2020 - 05/2002
4Glycoproteins (Glycoprotein)IBA
01/2020 - 01/2002
4LipopolysaccharidesIBA
01/2020 - 11/2003
4InterferonsIBA
01/2020 - 07/2013
4Toll-Like Receptors (Toll-Like Receptor)IBA
01/2018 - 01/2010
4Mineral Oil (Liquid Paraffin)FDA LinkGeneric
11/2017 - 12/2007
44- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA
11/2012 - 02/2007
4NADP (NADPH)IBA
07/2012 - 09/2005
3Cysteine (L-Cysteine)FDA Link
04/2024 - 10/2007
3Biomarkers (Surrogate Marker)IBA
01/2023 - 09/2013
3glycosylated collagenIBA
01/2022 - 07/2002
3LipidsIBA
01/2021 - 11/2017
3LigandsIBA
10/2020 - 08/2010
3Interleukin-17 (Interleukin 17)IBA
01/2020 - 01/2017
3NitrogenIBA
01/2020 - 09/2009
3SodiumIBA
03/2018 - 08/2014
3AsparagineIBA
01/2018 - 10/2007
3Acute-Phase Proteins (Acute-Phase Protein)IBA
11/2017 - 01/2002
3Proteoglycans (Proteoglycan)IBA
07/2017 - 06/2011
3Estrogens (Estrogen)FDA Link
11/2016 - 11/2003
3PolymersIBA
01/2016 - 11/2011
3poly-N-isopropylacrylamideIBA
01/2016 - 11/2011
3CitrullineIBA
10/2015 - 02/2009
3Immunodominant EpitopesIBA
11/2014 - 01/2006
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2006 - 02/2002
3Myelin-Oligodendrocyte GlycoproteinIBA
08/2004 - 07/2002
2Complement C5 (Complement 5)IBA
02/2024 - 09/2006
2IgG Receptors (Fc gamma RI)IBA
02/2024 - 01/2021
2Interleukin-10 (Interleukin 10)IBA
11/2023 - 01/2004
2NucleotidesIBA
06/2023 - 06/2011
2Arginine (L-Arginine)FDA Link
06/2023 - 11/2022
2Amino Acid Transport Systems (Amino Acid Transporter)IBA
01/2023 - 12/2015
2Mitochondrial DNA (mtDNA)IBA
01/2023 - 12/2009

Therapy/Procedure

9Therapeutics
01/2023 - 02/2002
4Intraperitoneal Injections
06/2023 - 09/2005
4Injections
05/2022 - 03/2005
3Intravenous Injections
05/2022 - 07/2004
3Transplantation
10/2010 - 06/2002